Pharmacological treatment for substance use disorder: A systematic review.
There is strong evidence of the substance dependence has a negative impact on key dimensions of health. The scientific evidence suggests that pharmacological treatment could play a fundamental role in […]
Cannabis use and atherosclerotic cardiovascular disease outcomes: A meta-analysis of multinational cohort data.
While an association between cannabis use and the risk of atherosclerotic cardiovascular diseases (ASCVD) has been reported numerous times, it remains inconclusive as to whether this link is causal in […]
Age of onset of cannabis use and substance use problems: A systematic review of prospective studies.
The association between the age of cannabis use (CU) onset and substance use (SU) problems has been extensively studied, yet findings remain inconsistent. This systematic review aimed to examine prospective […]
Evaluating Delta-8-THC-Induced Psychosis: A Systematic Review.
This study reviews literature on the psychiatric effects of delta-8-THC, particularly psychosis and severe mental health outcomes, to highlight the need for further research and regulation. Marijuana, the most widely […]
Cannabis use in Crohn’s disease: a systematic review and meta-analysis of randomized controlled trials (RCTs).
This meta-analysis aims to systematically evaluate the efficacy and safety of cannabis in the management of Crohn’s disease (CD) by synthesizing evidence from randomized controlled trials (RCTs). By adhering to […]
Effective interventions to prevent youth vaping behaviours: a rapid review.
To identify effective policies and non-policy interventions preventing youth vaping behaviour initiation and assess their effectiveness by the level of intrusiveness and subpopulations. This systematic rapid review followed the Preferred […]
Pulmonary langerhans cell histiocytosis secondary to Marijuana use: a case report and systematic review of the literature.
Pulmonary Langerhans Cell Histiocytosis (PLCH) is a rare interstitial lung disease primarily affecting young to middle-aged smokers. While traditionally linked to tobacco use, there is growing evidence that cannabis use […]
Impact of CB1 receptor antagonism on skeletal muscle hypertrophy and metabolic health: a systematic review of preclinical studies.
The endocannabinoid system (ECS), regulating such processes as energy homeostasis, inflammation, and muscle function, centers around cannabinoid receptors, including CB1. These receptors are mainly located in the central nervous system […]
Uncovering the Metabolic Footprint of New Psychoactive Substances by Metabolomics: A Systematic Review.
New psychoactive substances (NPSs) emerged in the 2000s as legal alternatives to illicit drugs and quickly became a huge public health threat due to their easy accessibility online, limited information, […]
Electronic cigarettes for smoking cessation.
Electronic cigarettes (ECs) are handheld electronic vaping devices that produce an aerosol by heating an e-liquid. People who smoke, healthcare providers, and regulators want to know if ECs can help […]
Cannabinoids for Acute Postoperative Pain Management: A Systematic Review and Meta-Analysis of Clinical Trials.
Poor acute postoperative pain control, coupled with the use of intravenous medications with a limited and unsafety efficacy spectrum, has led to new therapeutic alternative explorations to reduce adverse events […]
Cannabis consumption and risk of asthma: a systematic review and meta-analysis.
Cannabis is the third most widely used psychoactive substance globally, and its consumption has been increasing, particularly with the growing trend of legalization for medicinal and recreational use. Recent studies […]
Effects of prenatal cannabinoid use on the monoamine system in the fetoplacental unit: A systematic review of animal and human studies.
The rapid increase in cannabis use during pregnancy-up by 170 % between 2009 and 2016-raises pressing concerns about its effects on fetal health, particularly on the delicate monoamine system within the […]
The Effects of Cannabinoids on Ischemic Stroke-Associated Neuroinflammation: A Systematic Review.
Stroke represents a significant burden on global health and the economy, with high mortality rates, disability, and recurrence. Ischemic stroke is a serious condition that occurs when a blood vessel […]
Evaluating the association between cannabis decriminalization and legalization and cannabis arrests and related disparities: A Systematic review.
While a key goal of liberalizing cannabis policy is to reduce harms related to criminal justice involvement, the degree to which this occurs and how it varies by policy format […]
Cannabis use and HIV among Black sexually minoritized men: a systematic review and narrative analysis.
We conducted a systematic review evaluating the extant literature examining the impacts of cannabis use on HIV-related outcomes among Black sexual minoritized men (BSMM). A systematic review. We conducted a […]
The impact of cannabis on immune checkpoint inhibitor therapy: a systematic review of immunomodulatory effects of cannabis in patients with and without cancer.
Cannabis is commonly used among patients with cancer for palliative benefit. As the use of immune checkpoint inhibitors (ICIs) for cancer therapy increases, there is concern about potential interactions between […]
The association between cannabis and depression: an updated Systematic Review and Meta-analysis.
Cannabis is one of the most commonly used drugs globally, although its legal status varies across regions. Public support for its decriminalization has increased, but gaps in our understanding of […]