Recent cannabis use affects the association between baseline immune markers and long-term outcomes in psychosis.
Aberrant levels of blood markers reflecting inflammation and immune system activation have been implicated in psychotic disorders and linked to psychotic symptom severity. However, their predictive value for the long-term […]
The Effect of Chronic Liver Disease on Adverse In-Hospital Outcomes After Radical Cystectomy and Ileal Conduit Urinary Diversion.
Radical cystectomy (RC) is the gold standard treatment for muscle-invasive bladder cancer (BCa). Chronic liver disease (CLD) may predispose to worse in-hospital outcomes after RC and ileal conduit, but this […]
Cannabinoid 1 receptor availability in posttraumatic stress disorder: A positron emission tomography study.
The endocannabinoid system (ECS) plays a critical role in fear learning and maintenance and may, therefore, be implicated in the pathophysiology of posttraumatic stress disorder (PTSD). The exact role of […]
Role of Chronic Toxoplasmosis in Substance Abuse in Humans and its Effect on Dopamine Levels.
Toxoplasma gondii is a common parasitic infection agent that, in its chronic phase, forms persistent tissue cysts in neuronal cells, potentially leading to neurological and behavioral alterations. To investigate the […]
The impact of socioeconomic factors on the incidence and characteristics of first-episode psychosis.
The environment shapes the risk of psychosis. In particular, urbanicity, deprivation or inequality, migrant density and cannabis availability may not only influence psychosis incidence, but also the characteristics of individuals […]
Right heart failure outcomes in systemic lupus erythematosus: Cardiovascular insights from a nationwide inpatient study.
BackgroundPatients with Systemic Lupus Erythematosus (SLE) face a higher risk of cardiovascular morbidity, but data on Right Heart Failure (RHF) in-hospital outcomes in the context of SLE remain limited. Using […]
Episodic memory and inhibitory control in people who inject substances results of cohort COSINUS study.
Cognitive disorders associated with addictive disorders are well established in the literature for numerous substances and behaviours. Very few studies have examined the effect of polydrug use on cognitive functioning. […]
Cannabis impacts female fertility as evidenced by an in vitro investigation and a case-control study.
Cannabis consumption and legalization is increasing globally, raising concerns about its impact on fertility. In humans, we previously demonstrated that tetrahydrocannabinol (THC) and its metabolites reach the ovarian follicle. An […]
Mutual age-varying influences of binge drinking and cannabis use during emerging adulthood in the NCANDA cohort.
Binge drinking peaks during emerging adulthood and is associated with negative developmental outcomes. Within-person changes in cannabis use have been shown to coincide with binge drinking; however, whether within-person changes […]
Trends of metabolic syndrome among Iranian patients with diabetes and its association with cardiovascular disease and diabetes complications: a nationwide study of the National Program for Prevention and Control of Diabetes.
Metabolic syndrome (MetS) is highly prevalent among individuals with type 2 diabetes and is characterized by a combination of specific clinical parameters including abnormal blood lipid levels, impaired fasting glucose, […]
Genomic DNA methylation profile in peripheral blood of children with congenital biliary dilatation.
Congenital biliary dilatation (CBD) is a prevalent congenital biliary disease in children, particularly in Asian populations, yet its etiology remains poorly understood. This study aimed to investigate the genome-wide DNA […]
Cannabis use disorder and perioperative outcomes following complex cancer surgery.
Cannabis usage is increasing in the United States, especially among patients with cancer. We sought to evaluate whether cannabis use disorder (CUD) was associated with higher morbidity and mortality among […]
Emerging trends in nationwide mortality, limb loss, and resource utilization for critical limb ischemia in young adults.
Recent trends indicate a rise in the incidence of critical limb ischemia (CLI) among younger adults. This study examines trends in CLI hospitalization and outcomes among young adults with peripheral […]
Do traumatic events and substance use co-occur during adolescence? Testing three causal etiologic hypotheses.
Why do potentially traumatic events (PTEs) and substance use (SU) so commonly co-occur during adolescence? Causal hypotheses developed from the study of posttraumatic stress disorder (PTSD) and substance use disorder […]
Convolutional neural network for identifying common bile duct stones based on magnetic resonance cholangiopancreatography.
To develop an auto-categorization system based on machine learning for three-dimensional magnetic resonance cholangiopancreatography (3D MRCP) to detect choledocholithiasis from healthy and symptomatic individuals. 3D MRCP sequences from 254 cases […]
Evaluation of three-year neurodevelopmental outcomes in infants prenatally exposed to substance use.
Prenatal exposure to substance use is associated with long-term deficits in the neurodevelopment of children. The objective was to investigate the association between cognitive, motor, and language neurodevelopment at three […]
Clinical predictors of significant findings on EUS for the evaluation of incidental common bile duct dilation.
Although EUS is highly accurate for the evaluation of common bile duct (CBD) dilation, the yield of EUS in patients with incidental CBD dilation is unclear. Serial patients undergoing EUS […]
The risk of cannabis use disorder is mediated by altered brain connectivity: A chronnectome study.
The brain mechanisms underlying the risk of cannabis use disorder (CUD) are poorly understood. Several studies have reported changes in functional connectivity (FC) in CUD, although none have focused on […]