Clinician’s perceptions and experiences with tobacco treatment in people who use cannabis: a qualitative study.
Global demand for the treatment of cannabis use disorder has increased significantly, prompting a need to understand effective strategies for addressing concurrent cannabis and tobacco use. This study focuses on […]
Mitochondrial DNA variants and their impact on epigenetic and biological aging in young adulthood.
The pace of biological aging varies between people independently of chronological age and mitochondria dysfunction is a key hallmark of biological aging. We hypothesized that higher functional impact (FI) score […]
Longitudinal evolution of the transdiagnostic prodrome to severe mental disorders: a dynamic temporal network analysis informed by natural language processing and electronic health records.
Modelling the prodrome to severe mental disorders (SMD), including unipolar mood disorders (UMD), bipolar mood disorders (BMD) and psychotic disorders (PSY), should consider both the evolution and interactions of symptoms […]
Machine Learning-Guided Fluid Resuscitation for Acute Pancreatitis Improves Outcomes.
Ariel Dynamic Acute Pancreatitis Tracker (ADAPT) is an artificial intelligence tool using mathematical algorithms to predict severity and manage fluid resuscitation needs based on the physiologic parameters of individual patients. […]
The comparative effectiveness of medicinal cannabis for chronic pain versus prescription medication treatment.
Reviews of the effectiveness of medicinal cannabis for chronic pain vary in their conclusions. IASP has identified that a key missing evidence in this debate is data from observational cohort […]
Combined oral contraceptives are associated with increased risk of developing gastroparesis in pre-menopausal women.
Females are disproportionately affected by gastroparesis. Sex hormones play a significant role. The aim of this study was to investigate the effects of combined oral contraceptives (COC) on the development […]
Changes in population-level alcohol sales after non-medical cannabis legalisation in Canada.
There is considerable interest in whether individuals substitute cannabis for alcohol and in legalisation’s potential to reduce or increase alcohol-attributable harms. This study aimed to determine whether non-medical cannabis legalisation […]
Family incarceration and adolescent nicotine, alcohol, and cannabis use: A coarsened exact matching approach.
Evidence overwhelmingly indicates that adverse childhood experiences (ACE), a set of highly correlated traumatic events experienced before age 18, increase risk for adolescent substance use. However, few studies have examined […]
Changes in Incident Schizophrenia Diagnoses Associated With Cannabis Use Disorder After Cannabis Legalization.
Despite public health concerns that cannabis legalization may increase the number of cases of schizophrenia caused by cannabis, there is limited evidence on this topic. To examine changes in the […]
Illegal drug use amongst male UK military personnel who sustained physical combat injuries: The ADVANCE cohort study.
Illegal drug use may be a consequence of sustaining a serious physical combat injury, though no known research has investigated this in a UK setting. This analysis utilises the baseline […]
Cannabis Use Disorder Emergency Department Visits and Hospitalizations and 5-Year Mortality.
Cannabis use disorders (CUD) are associated with adverse health effects, including mental disorders and motor vehicle collision-related injuries. However, little is known about whether CUDs are associated with increased mortality […]
Protective Factors Against e-Cigarette Use Among First Nations People Aged 16-24 in the Next Generation Youth Wellbeing Study.
Adolescent e-cigarette use is increasing and is associated with subsequent smoking. This study examines potential protective factors associated with not vaping among First Nations adolescents in Australia to inform community […]
Multi-level socioeconomic modifiers of the comorbidity of post-traumatic stress and tobacco, alcohol, and cannabis use: the importance of income.
Post-traumatic stress (PTS) symptoms are highly comorbid with substance use (i.e., alcohol, tobacco, and cannabis). Few studies have investigated potential individual-, household-, and neighborhood-level socioeconomic effect modifiers of this comorbidity […]
Validation of Laboratory Risk Indicator for Necrotizing Fasciitis (LRINEC) score and establishment of novel score in Japanese patients with necrotizing fasciitis (J-LRINEC score).
The Laboratory Risk Indicator for Necrotizing Fasciitis (LRINEC) score is widely used to distinguish between necrotizing fasciitis and cellulitis. However, LRINEC scores are not as sensitive or specific as initially […]
Exploring the relationship between sleep patterns, alcohol and other substances consumption in young adults: Insights from wearables and Mobile surveys in the National Consortium on alcohol and NeuroDevelopment in adolescence (NCANDA) cohort.
The use of psychotropic substances has negative short- and long-term health outcomes, including complex direct and indirect effects on sleep and sleep-cardiovascular function. Here, we investigate daily relationships between self-reported […]
Evaluating maternal drug use disparities, risk factors and outcomes in Northeast Arkansas: a pre, during, and post-COVID-19 pandemic analysis.
The use of addictive substances remains a major health problem in the U.S. An increase in drug overdose and mortality was observed during the COVID-19 pandemic, especially in underserved populations. […]
Alcohol use in Early Midlife: Findings from the Age 37 Follow-Up Assessment of the FinnTwin12 Cohort.
This paper provides an overview of the most recent assessment, collected in early midlife, of the FinnTwin12 cohort, a population-based study of Finnish twins born in 1983-1987. The twins were […]
Cannabis use across the menstrual cycle: The impact of negative affect and cannabis use motives.
Women experience greater state negative affect (NA) and physical symptoms during the premenstrual and menstrual phases of the menstrual cycle. Although women use more cannabis during the premenstrual and menstrual […]