Sloughing esophagitis (esophagitis dissecans superficialis) is a benign, self-limited condition of uncertain etiology. It is most common in adults; pediatric literature is limited. Ten years of records were queried for esophageal biopsies containing terms “sloughing” and/or “dissecans.” Histologic inclusion criteria were “two-tone” appearance, sloughing/flaking of superficial epithelium, and parakeratosis. Degree of inflammation was documented and medical records were reviewed. Fourteen patients were identified ranging from 1 to 19 years (mean = 14 years) and included 3 males and 11 females.
