Gastroparesis (GP), cyclic vomiting syndrome (CVS), and cannabinoid hyperemesis syndrome (CHS) are chronic disorders of gut-brain motility. Though GP, CVS, and CHS are relatively common, recent, large scale data on their incidence and acute management are lacking. Thus, we sought to assess the incidence, rates of admission, medication administrations, and demographic data among emergency department (ED) visits for GP, CVS, and CHS in the United States.