Cannabidiol (CBD) may alleviate Parkinson’s disease (PD) symptoms, but its cognitive and anti-inflammatory effects remain unclear due to limited randomized trials. This study evaluates CBD’s efficacy in PD patients. Sixty PD patients were randomized into CBD (n = 30) or placebo (n = 30) groups. The CBD group received a sublingual CBD-enriched product (101.9 mg/ml CBD, 4.8 mg/ml tetrahydrocannabinol [THC]). The primary outcome was improvement in the Montreal Cognitive Assessment (MoCA) delayed recall scores.
